Superficial Necrolytic Dermatopathy

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  • Also known as diabetic dermatopathy, hepatocutaneous syndrome
  • In older dogs with diabetes mellitus, hepatic dysfunction or pancreatic lesions
  • Grossly: scaling and crusting, erythema, facial, genital and distal extremities alopecia, crusting, fissures and ulceration of foot pads
  • Microscopically: trilaminar thickening of epidermis (outermost layer is keratotic, intermediate oedematous and vacuolated, inner is hyperplastic)