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| − | | + | #redirect[[Intersex#Testicular feminisation]] |
| − | == Aetiology ==
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| − | * Genotype XY as should be in the male.
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| − | * Testes develop normally and secrete Androgens and MIH
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| − | * Foetal genetalia are genetically insensitive to the actions of Androgens due to a point mutation in the Androgen receptor.
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| − | == Consequence ==
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| − | * Wolffian Ducts regress, allowing formation of '''female external genetalia''':
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| − | ** Labia
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| − | ** Clitoris
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| − | ** Vagina
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| − | * Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression.
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| − | * Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''.
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| − | [[Category:Reproductive Disorders]] | |