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| − | <big><center>[[Reproductive System|'''BACK TO REPRODUCTIVE SYSTEM''']]</center></big>
| + | #redirect[[Intersex#Testicular feminisation]] |
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| − | <big><center>[[Reproductive_System#Fertilisation.2C_Implantation_and_Early_Embryonic_Development|'''BACK TO FERTILISATION , IMPLANTATION and EARLY EMBRYONIC DEVELOPMENT''']]</center></big>
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| − | <big><center>[[Fertilisation%2C_Implantation_and_Early_Embryonic_Development_-Sexual_Differentiation-_Anatomy_%26_Physiology#Associated_Disorders|'''BACK TO SEXUAL DIFFERENTIATION''']]</center></big>
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| − | == Aetiology ==
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| − | * Genotype XY as should be in the male.
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| − | * Testes develop normally and secrete Androgens and MIH
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| − | * Foetal genetalia are genetically insensitive to the actions of Androgens due to a point mutation in the Androgen receptor.
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| − | == Consequence ==
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| − | * Wolffian Ducts regress, allowing formation of '''female external genetalia''':
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| − | ** Labia
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| − | ** Clitoris
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| − | ** Vagina
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| − | * Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression.
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| − | * Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''.
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