Changes

Also Known As: '''''VES — Calicivirus infection — San Miguel Sea Lion Disease

Also Known As: '''''VES — Calicivirus infection — San Miguel Sea Lion Disease

'''Differentiation from [[Vesicular Stomatitis Virus]], [[Swine Vesicular Disease]] and [[Foot and Mouth Disease]] was imperative.'''

'''Differentiation from [[Vesicular Stomatitis Virus]], [[Swine Vesicular Disease]] and [[Foot and Mouth Disease]] was imperative.'''

'''Innoculation''' could be used as a method of differentiation but was time-consuming and innoculum supply was inconsistent. Thus, serological methods took over. '''Serum neutralisation, complement fixation and agar gel precipitation''' were all be used. '''PCR''' is also now available.

'''Innoculation''' could be used as a method of differentiation but was time-consuming and innoculum supply was inconsistent. Thus, serological methods took over. '''Serum neutralisation, complement fixation and agar gel precipitation''' were all used. '''PCR''' is also now available.

Histopathology of lesions revealed '''squamous epithelial swelling, pyknosis and karryorhexis'''. As cells died, the virus spread to neighbouring cells. Epithelial cells that were left intact usually showed evidence of '''degeneration and intracellular oedema'''. Haemorrhage and oedema were also seen in the subcutaneous tissues. The '''malphigian layer of the dermis''' where the virus primarily replicated became '''infiltrated with neutrophils and was thus weakened and oedematous, causing the upward displacement of the epidermis above it and thus the characteristic vesicle.'''

Histopathology of lesions revealed '''squamous epithelial swelling, pyknosis and karryorhexis'''. As cells died, the virus spread to neighbouring cells. Epithelial cells that were left intact usually showed evidence of '''degeneration and intracellular oedema'''. Haemorrhage and oedema were also seen in the subcutaneous tissues. The '''malphigian layer of the dermis''' where the virus primarily replicated became '''infiltrated with neutrophils and was thus weakened and oedematous, causing the upward displacement of the epidermis above it and thus the characteristic vesicle.'''

|date = 20 July 2011

|date = 20 July 2011

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[[Category:Pig Viruses]]

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