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New page: == Introduction == Parasitic gastroenteritis (PGE) is a disease complex associated with a number of nematode species (mostly strongyles), either singly or in combination. It is characteri...

== Introduction ==
Parasitic gastroenteritis (PGE) is a disease complex associated with a number of nematode species (mostly strongyles), either singly or in combination. It is characterised by:
*diarrhoea
*less than optimum productivity (sub-clinical disease)
*seasonal appearance
*hypoalbuminaemia.

PGE is of considerable economic importance in grazing livestock. It is a potential welfare problem, particularly on organic farms. Losses are associated with the cost of:
*replacement stock
*disruption of breeding programme
*impaired productivity, e.g. weight-gain, wool clip, milk yield, etc.
*treating clinically affected stock, e.g. drugs, labour, veterinary bills
*prophylaxis (prevention), e.g. drugs, labour, pasture management.


== Aetiology ==
Strongyle nematodes are the main cause of PGE in grazing animals and, in particular, those found in two superfamilies, i.e. '''Trichostrongyloidea''' and '''Strongyloidea'''. Non-bursate nematodes are rarely responsible for PGE, although ''Strongyloides'' species (a member of the family Rhabditoidea and NOT a strongyle) may sometimes contribute to the disease.

Normally, only a few of the many roundworm species that are found in the alimentary tract of grazing stock are important as causes of PGE, e.g. in first season calves in northern Europe, ''Ostertagia'' species (an abomasal nematode) is the primary pathogen with ''Cooperia'' and ''Nematodirus'' species (intestinal nematodes) acting as contributory factors; other worms are rarely of clinical significance.


== Epidemiology ==
=== Introduction ===
The epidemiology and pathogenesis of many strongyle infections of grazing animals are very similar. Infection by ingestion of an infective larva (L3), development to L4 and adult stages is generally restricted to gastric or intestinal mucosa (although a few species migrate around the body), adult worms eventually emerge to lie on the mucosal surface. The prepatent period is normally 2weeks, though may be 6+months for certain species or if development is "arrested".

'''Risk of disease''' depends on the balance between:
*'''rate of infection''' if the host; and
*'''host immunity'''.


=== Rate of Infection ===
The rate of infection of the host by infective L3 depends upon:
*host appetite (under normal circumstances this is fairly constant, increasing with host liveweight); and
*numbers of infective larvae (L3) on pasture (there are marked fluctuations in the number of L3 on pasture grazed by livestock during the year which help to explain the seasonal occurence of PGE).
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