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Image:LH_Lymphocyte_Histology.jpg|<div style="text-align: center;"><p>'''Lymphocyte'''</p><sup>©RVC 2008</sup></div>
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Image:LH_Lymphocytes_Histology.jpg|<div style="text-align: center;"><p>'''Lymphocytes'''</p><sup>©RVC 2008</sup></div>
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==Introduction==
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Lymphocytes account for around a third of all circulating [[Leukocytes|leukocytes]] and are formed in a variety of lymphoid tissues. They are functionally divided into [[#T cells|T cells]], [[#B cells|B cells]] and [[#Natural Killer (NK) Cells|NK (Natural Killer) cells]]. Lymphocytes vary in size (6-30µm) and are classified as small, medium or large. Large cells are either activated lymphocytes or NK cells. The vast majority of circulating lymphocytes are small and of a similar size to erythrocytes. Histologically they are round with a densely staining nucleus and a thin, often indistinct, rim of cytoplasm.  While NK cells can be distinguished by their large granules and kidney shaped nucleus, B and T cells appear the same histologically.</p>
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<p>Lymphocytes, along with associated supporting cells, form the immune system and recognise antigens, produce antibodies and destroy pathogens.</p>
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==Development==
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<p>Both T and B lymphocytes develop from a common stem cell ([[Haematopoiesis - Overview#Colony Forming Units|CFU-L's]]) and for a general overview of this process see [[Leukopoiesis#Lymphopoiesis|here]].</p>
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<p> Follow these links for a more detailed explanation on [[T cell differentiation - WikiBlood|T cell development]] and [[B cell differentiation - WikiBlood|B cell development]].</p>
      
==T cells==
 
==T cells==
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[[Basophils|Basophils]], [[Eosinophils|Eosinophils]], [[Lymphocytes|Lymphocytes]], [[Macrophages|Macrophages]], [[Mast Cells|Mast cells]], [[Monocytes|Monocytes]] & [[Neutrophils|Neutrophils]] |  [[Thrombocytes|Thrombocytes]] & [[Thrombopoiesis#Megakaryocyte|Megakaryocytes]]</sup></b></center>
 
[[Basophils|Basophils]], [[Eosinophils|Eosinophils]], [[Lymphocytes|Lymphocytes]], [[Macrophages|Macrophages]], [[Mast Cells|Mast cells]], [[Monocytes|Monocytes]] & [[Neutrophils|Neutrophils]] |  [[Thrombocytes|Thrombocytes]] & [[Thrombopoiesis#Megakaryocyte|Megakaryocytes]]</sup></b></center>
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[[Category:Blood_Cells]][[Category:Lymphoreticular System]]
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[[Category:Blood_Cells]][[Category:Lymphoreticular System|X]]
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