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==Transmission and Epidemiology==
 
==Transmission and Epidemiology==
Houe, 1999 Kirkland et. al, 1991
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In most countries, BVDV is endemic and studies detecting antibody have estimated that between 70 and 100% of herds are either currently infected or have recently been infected with bovine viral diarrhoea virus<sup>23</sup>.
 
In most countries, BVDV is endemic and studies detecting antibody have estimated that between 70 and 100% of herds are either currently infected or have recently been infected with bovine viral diarrhoea virus<sup>23</sup>.
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BVDV can be transmitted from infected to susceptible cattle in several ways. Firstly, direct contact with a virus-shedding animal can cause disease. Both acutely and persistently infected animals shed virus, but levels of shedding are much higher in persistently infected cattle and transmission is more efficient. Transmission to heifers and cows may also occur venereally or via artificial insemination as acutely and persistently unfected bulls sheed bovine viral diarrhoea virus in their semen<sup>24</sup>. The testes is an immunoprivileged site, and the virus can persist in this location despite otherwise systemic clearance<sup>25</sup>.  
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BVDV can be transmitted from infected to susceptible cattle in several ways. Firstly, direct contact with a virus-shedding animal can cause disease. Both acutely and persistently infected animals shed virus, but levels of shedding are much higher in persistently infected cattle and transmission is more efficient. Transmission to heifers and cows may also occur venereally or via artificial insemination as acutely and persistently unfected bulls sheed bovine viral diarrhoea virus in their semen<sup>24</sup>. The testes is an immunoprivileged site, and the virus can persist in this location despite otherwise systemic clearance<sup>25</sup>. Indirect spread is possible: BVDV has been shown to spread through the re-use of needles, nose tongs<sup>26</sup> and rectal gloves<sup>27</sup>, and blood feeding flies also give transmission.
 
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Virus may also be spread indirectly. Use of live or infected vaccines and reuse of needles, nose tongs (Gunn, 1993) or rectal gloves (Lang-Ree et al., 1994) may cause transmission. Blood feeding flies may also spread BVDV (Tarry et. al, 1991).
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===Epidemiology===
 
===Epidemiology===
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