Cryptococcus neoformans

From WikiVet English
Jump to navigation Jump to search
  • Cryptococcus neoformans causing Cryptococcosis
  • Causes a granulomatous rhinitis, gelatinous exudate, granulomatous pneumonia
  • Nodules or destructive masses which often result in facial swelling
  • In severe cases, extension from nasal cavity to involve skin and oral mucosa can occur
  • Can invade through adjacent structures, eg: through the cribiform plate into the brain! These cases therefore can present as a primary neurological disease.
  • Microscopic:
    • Large number of fungi and only few macrophages, lymphocytes and giant cells