Hyperparathyroidism Flashcards

Question	Answer		Article
What are the two types of primary hyperparathyroidism and which is most common?	Glandular hyperplasia and Neoplasia Neoplasia is most common in the form of benign solitary adenoma		Link to Article
What are the two types of secondary hyperparathyroidism and how are they caused?	Renal – caused by hyperphosphataemia due to reduced GFR Nutritional – due to excess phosphorus ingestion or vitamin D3 deficiency		Link to Article
In what species is secondary renal hyperparathyroidism most common?	Dogs		Link to Article
What is the most important metabolic disturbance caused by hyperparathyroidism and what are the clinical signs?	Hypercalcaemia PUPD Anorexia Lethargy Depression Constipation Shivering Vomiting Stiff gait Weakness		Link to Article
How is fibrous osteodystrophy caused?	Ingestion of excessive phosphorus binds calcium in the gut preventing absorption and causes release of PTH Bone is broken down by osteoclastic activity under the action of PTH The flat bones of the skull are affected first Fibrous tissue is laid down over the weakened bone in an attempt by the body to regain some strength Leaves bones brittle, prone to fracture and avulsions and often deformed		Link to Article
What abnormality is often detectable in urine in animals with hyperparathyroidism?	Increased amounts of phosphorus and sometimes calcium		Link to Article
What is different on a blood biochemistry panel in an animal with nutritional secondary HTP compared to any other kind?	Low or normal calcium compared to high		Link to Article
How should horses with bran disease be treated?	Confined until radiographs are normal Fed 1:1-3:1 ratio of Ca:P Fed low oxalates or supplemented with limestone		Link to Article