Idiopathic Polyradiculoneuritis
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Idiopathic Polyradiculoneuritis
- Immune mediated demyelination often involving roots, directed against unknown epitopes in peripheral myelin.
- May be post infection
- May get axonal injury if severe
- As for distal denervating (although more rapid onset)
- May have sensory involvement.
- By clinical signs
- CSF changes if roots involved
- Slower nerve conduction
- H reflexes and F-waves may be lost
- Very good prognosis
- Recovery in 3-6 weeks by remyelination
- Immunosuppresive levels of corticosteroids (although may delay remyelination)