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Puberty Endocrine Events - Anatomy & Physiology (view source)
Revision as of 18:37, 8 December 2010
, 18:37, 8 December 2010no edit summary
== Hypothalamic Neuron Release of GnRH ==
= Hypothalamic Neuron Release of GnRH =
* Hypothalamic development occurs gradually with growth of the animal.
* Hypothalamic development occurs gradually with growth of the animal.
== Female ==
=== Female ===
* The [[Hypothalamus_- Anatomy & Physiology|Hypothalamus]] contains a tonic GnRH centre and a preovulatory GnRH 'surge' centre.
* The [[Hypothalamus_- Anatomy & Physiology|Hypothalamus]] contains a tonic GnRH centre and a preovulatory GnRH 'surge' centre.
* The sensitivity of the surge centre never changes. Puberty is triggered because the sensitivity of the tonic centre to negative feedback decreases. This allows smaller quantities of oestrogen to stimulate the release of GnRH and thus LH and FSH. These gonadotrophins then stimulate [[Follicles - Anatomy & Physiology|follicles]], so that more and more oestrogen is produced until it is sufficient to trigger the surge centre to release the pre-ovulatory surge of GnRH.
* The sensitivity of the surge centre never changes. Puberty is triggered because the sensitivity of the tonic centre to negative feedback decreases. This allows smaller quantities of oestrogen to stimulate the release of GnRH and thus LH and FSH. These gonadotrophins then stimulate [[Follicles - Anatomy & Physiology|follicles]], so that more and more oestrogen is produced until it is sufficient to trigger the surge centre to release the pre-ovulatory surge of GnRH.
== Male ==
=== Male ===
* Does not develop a surge centre.
* Does not develop a surge centre.
** Fatty acid sensitive neurons
** Fatty acid sensitive neurons
== Leptin ==
=== Leptin ===
* Leptin is a hormonal peptide produced by adipocytes (fat cells).
* Leptin is a hormonal peptide produced by adipocytes (fat cells).
* Leptin may be a signal that notifies GnRH neurons directly that nutritional status is adequate because a threshold 'fatness' has been achieved. Leptin may also signal to GnRH neurons indirectly via stimulation of neuropeptide Y, which in turn stimulates GnRH neurons.
* Leptin may be a signal that notifies GnRH neurons directly that nutritional status is adequate because a threshold 'fatness' has been achieved. Leptin may also signal to GnRH neurons indirectly via stimulation of neuropeptide Y, which in turn stimulates GnRH neurons.
== Glucose ==
=== Glucose ===
* Blood glucose stimulate glucose sensing neurons.
* Blood glucose stimulate glucose sensing neurons.
* Glucose sensing neurons stimulate GnRH neurons to produce GnRH.
* Glucose sensing neurons stimulate GnRH neurons to produce GnRH.
== Blood Fatty Acids ==
=== Blood Fatty Acids ===
* Blood fatty acids stimulate neurons that in turn stimulate GnRH neurons.
* Blood fatty acids stimulate neurons that in turn stimulate GnRH neurons.
[[Category:Reproductive System]]
[[Category:Puberty]][[Endocrine System - Anatomy & Physiology]]