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See [[Avian Liver - Anatomy & Physiology|avian liver]]
 
See [[Avian Liver - Anatomy & Physiology|avian liver]]
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==Histology==
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[[Image:Lobule Histology.jpg|thumb|right|150px|Liver Lobule Histology - Copyright RVC 2008]]
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*Connective tissue capsule around each lobule
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*Thin mesothelium covers connective tissue layer
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*The larger liver cells are called lobules
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**Each lobule contains an opening for the central vein and contains portal areas
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**Lobules composed of liver cords called hepatocytes
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**Sinusoids present between hepatocytes containing red blood cells
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*Portal area present in lobules
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**Hepatic artery- thick walls, small diameter
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**Hepatic vein- thin walls, large and irregular shape
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**Bile ducts- cuboidal or columnar epithelium
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**Lymphatics- small and delicate
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[[Image:Portal Triad Histology.jpg|thumb|right|150px|Portal Triad Histology in a Lobule- Copyright RVC 2008]]
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*Hepatocytes are the smaller liver cells in the lobules
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**Contain glycogen granules
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**Stain pink as are eosinophilic
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**Spherical nucleus
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**Forms cords called branching plates (lamellae)
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**Upper and lower margins are tight junctions
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**3 functioning surfaces
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***Adjacent to sinusoid contains microvilli
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***Between adjacent cells are smooth
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***Adjacent cells have short microvilli, membranes diverge, explanded intracellular spaces and bile canaliculi
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*Kupfer macrophages present near the lining of the sinusoids
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===Acinus===
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*the smallest functional unit of the [[Liver - Anatomy & Physiology|liver]] - this unit stresses the dependence of the [[Liver - Anatomy & Physiology|liver]] on its afferent blood vessels and efferent bile ducts
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*a roughly diamond shaped parenchymal mass surrounding and supplied by the portal area
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*consists of 3 zones:
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**Zone 1 - periportal (centroacinar), around the portal areas
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**Zone 2 - midzonal
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**Zone 3 - centrilobular (periacinar), bordering the hepatic venules
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NB: blood enters from Zone 1 to Zone 3 and thus becomes less and less oxygenated
    
==Links==
 
==Links==
    
'''Test yourself with the [[Liver - Anatomy & Physiology - Flashcards|Liver & Gall Bladder Flashcards]]'''
 
'''Test yourself with the [[Liver - Anatomy & Physiology - Flashcards|Liver & Gall Bladder Flashcards]]'''
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'''Click here for information on [[Liver - Histology|liver histology]]'''
      
'''Click here for information on [[:Category:Liver - Pathology|pathology of the Liver]]'''
 
'''Click here for information on [[:Category:Liver - Pathology|pathology of the Liver]]'''
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