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Corrected typo ("Hepatotoxixity" is now "Hepatotoxicity.")
* Sulphonamides inhibit thyroid gland function and so mild signs of hypothyroidism have been seen in dogs that have had intesive dosage regimens.
* Sulphonamides inhibit thyroid gland function and so mild signs of hypothyroidism have been seen in dogs that have had intesive dosage regimens.
===Hepatotoxixity===
===Hepatotoxicity===
*some of these casue hepatic necrosis in susceptible animals
*some of these casue hepatic necrosis in susceptible animals
*has been associated with a reduced capability of detoxifying the metabolites
*has been associated with a reduced capability of detoxifying the metabolites