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==Adrenal Glands==
 
==Adrenal Glands==
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3. zona reticularis
 
3. zona reticularis
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These zones all produce hormones derived from cholesterol, which is abundant in the cells. The '''adrenal cortex''' represents 80-90% of the adrenal gland.  
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All these zones produce hormones derived from cholesterol, which is abundant in the cells. The '''adrenal cortex''' represents 80-90% of the adrenal gland.  
    
The '''adrenal medulla''' is primarily involved in the production of catecholamines; epinephrine and norepinephrine. In fetal life, the adrenal medulla plays a role in the autonomic nervous system. The medulla acts as a sympathetic ganglion with the postganglionic cells lacking axons. Through sympathetic preganglionic fiber stimulation, the medullary cells secrete catecholamines. The adrenal medulla represents only 10-20% of the adrenal gland.
 
The '''adrenal medulla''' is primarily involved in the production of catecholamines; epinephrine and norepinephrine. In fetal life, the adrenal medulla plays a role in the autonomic nervous system. The medulla acts as a sympathetic ganglion with the postganglionic cells lacking axons. Through sympathetic preganglionic fiber stimulation, the medullary cells secrete catecholamines. The adrenal medulla represents only 10-20% of the adrenal gland.
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<gallery>
 
<gallery>
Image:Histology of the Adrenal Glands..jpg|<small>'''Histological section of the Adrenal Gland. (RVC 2008)</small>
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Image:Histology of the Adrenal Glands..jpg|<small>'''Histological section of the Adrenal Gland, from the [[Endocrine Histology resource|Histology of the Endocrine system tutorial]]</small>
Image:Histology of the Adrenal Glands showing zones..jpg|<small>'''Histological section of the Adrenal Gland Cortical zones. (RVC 2008)</small>
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Image:Histology of the Adrenal Glands showing zones..jpg|<small>'''Histological section of the Adrenal Gland Cortical zones, from the [[Endocrine Histology resource|Histology of the Endocrine system tutorial]]</small>
Image:Histology of the Adrenal Glands Medulla..jpg|<small>'''Histological section of the Adrenal Gland showing Medulla and Zona Reticularis (RVC 2008)</small>
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Image:Histology of the Adrenal Glands Medulla..jpg|<small>'''Histological section of the Adrenal Gland showing Medulla and Zona Reticularis, from the [[Endocrine Histology resource|Histology of the Endocrine system tutorial]]</small>
 
</gallery>
 
</gallery>
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==Functional anatomy==
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[[Image:Normal adrenal cortex.jpg|right|thumb|125px|<small><center>'''Normal Adrenal Cortex'''. Courtesy of A. Jefferies</center></small>]]
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The adrenal glands are essential to life.
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They are closely applied to the cranial poles of each kidney.  Consists of a cortex and medulla, each having different embryological origin.  In some lower animals the two components actually exist as separate endcrine glands.
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*'''Cortex''': Secretes a variety of steroid hormones derived from ''cholesterol''. 
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**''Zona glomerulosa'': Secretes '''Aldosterone'''.  Concerned with electrolyte and fluid homeostasis.
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**''Zona Fasciculata'': Secretes '''Glucocorticoids'''.  Controls metabolism of lipid, protein and carbohydrate.
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**''Zona Reticularis'': Produces '''Sex hormones'''.  Supplements gonadal sex hormone secretion.
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*'''Medulla''': Embryologically similar origin to the sympathetic nervous system.  Secretes ''catecholamine hormones'' E.g. Adrenaline, noradrenaline.<br>
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Secretion from the medulla is directly controlled by the sympathetic nervous
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system, allowing a rapid response.  In contrast, the secretions from the cortex are controlled by the hormones ACTH and other circulating hormones.
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As with any endocrine gland there are two main types of pathology:
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*Insufficiency leading to [[Hypoadrenocorticism|'''Addisons disease''']].
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*Excess leading to [[Hyperadrenocorticism|'''Cushings disease''']].
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{{Template:Learning
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|powerpoints = [[Endocrine Histology resource|Histology of the Endocrine system]]
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|OVAM = [http://www.onlineveterinaryanatomy.net/content/ovine-adrenal-gland-histology Ovine Adrenal Gland Histology 1]<br>[http://www.onlineveterinaryanatomy.net/content/ovine-adrenal-gland-histology-zona-fasiculate-and-zona-glomerulosa Ovine Adrenal Gland Histology 2]
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|Vetstream = [https://www.vetstream.com/canis/search?s=adrenals Adrenal diseases]
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}}
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==Webinars==
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<rss max="10" highlight="none">https://www.thewebinarvet.com/endocrinology/webinars/feed</rss>
    
[[Category:Endocrine System - Anatomy & Physiology]]
 
[[Category:Endocrine System - Anatomy & Physiology]]
 
[[Category:A&P Done]]
 
[[Category:A&P Done]]

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