''Clostridium perfringens, C. difficile'' and ''C. spireforme'' produce toxins causing oedema, haemorrhage, mucosal dysfunction and necrosis. Clostidial enteritis manifests as 2 syndromes. The first is acute diarrhoea that is likely to have been caused by dietary changes, antibiotic therapy, concurrent diseases or physiological stresses. The second manifestation occurs in older (>6months) hamsters where they slowly loose weight and condition and die without diarrhoea.<br />