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Hamsters (Laboratory) - Pathology (view source)
Revision as of 15:40, 6 January 2011
, 15:40, 6 January 2011→Infectious Causes of Diarrhoea
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Microscopic pathology includes lesions in the small intestine and cecum together with serosal oedema. There will also be submucosal oedema and effacement of enterocytes colonised by bacteria in the small intestine or cecum. Often there is no inflammatory cell inflitrate in the lamina propria or submucosa.
Microscopic pathology includes lesions in the small intestine and cecum together with serosal oedema. There will also be submucosal oedema and effacement of enterocytes colonised by bacteria in the small intestine or cecum. Often there is no inflammatory cell inflitrate in the lamina propria or submucosa.
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'''Ileitis'''
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Causative agents include ''Campylobacter coli'' and chlamydial organisms transmitted via fecal-oral or fomite contamination. Clinical signs include lethargy, anorexia, diarrhoea, dehydration and death. Moist faeces often stains the base of the tail. Ileitis primarily occurs in hamsters of between 3 to 10 weeks.
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Microscopic pathology includes lesions in the ileum and cecum and serosal haemorrhage. The ileum is often also thickened. Intestinal segments will have mild to moderate segmental hyperplasia of the mucosa. Intestinal crypts will appear elongated with marked proliferation of enterocytes and often goblet cells. Lymphoid hyperplasia may be seen together with leukocytes near the base of the villi. Diagnosis is primarily made via histolology.
'''Salmonella'''
'''Salmonella'''
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