Changes

'''Chondrocytes'''

'''Chondrocytes'''

Reside within '''lacunae''' within ECM and are responsible for synthesizing the '''matrix'''. The matrix consists of type II collagen, (except fibrocartilage) and proteoglycans with associated glycosaminoglycans. They are continually turned over and are the most vulnerable component of cartilage. Decresed proteoglycan, causes loss of lubrication which results in collagen disruption. This includes, frays, clefts, fibrillation, ulcers, exposure of bone, [[Musculoskeletal Terminology - Pathology|eburnation, +/- osteophytes and joint mice]].  

Reside within '''lacunae''' within ECM and are responsible for synthesizing the '''matrix'''. The matrix consists of type II collagen, (except fibrocartilage) and proteoglycans with associated glycosaminoglycans. They are continually turned over and are the most vulnerable component of cartilage. Decreased proteoglycan, causes loss of lubrication which results in collagen disruption. This includes, frays, clefts, fibrillation, ulcers, exposure of bone, [[Musculoskeletal Terminology - Pathology|eburnation, +/- osteophytes and joint mice]].  

Cartilage is avascular, nutrients and waste move via diffusion. The perichondrium surrounding the cartilage is composed of two layers:

Cartilage is avascular, nutrients and waste move via diffusion. The perichondrium surrounding the cartilage is composed of two layers:

2. '''Chondrogenic'''- inner, flattened cells that differentiate to chondrocytes.

2. '''Chondrogenic'''- inner, flattened cells that differentiate to chondrocytes.

==Types of Cartilage==

==Types of Cartilage==

===Hyaline Cartilage===

===Hyaline Cartilage===

The most abundant in the body. It is normally blue-white, smooth with a moist surface and turns yellow and becomes thinner in old age. It is found in nose, trachea, bronchi, ventral ends of ribs and sternal attachment. It is surrounded by perichondrium. It is at sites of articulation to provide a resilient, frictionless surface that resists compression. It is also found at epiphyseal growth plates.

Hyaine cartilage is the most abundant in the body and surrounded by perichondrium. It is normally blue-white, smooth with a moist surface and turns yellow and becomes thinner in old age. It is found in nose, trachea, bronchi, ventral ends of ribs and sternal attachment. It provides a resilient, frictionless surface that resists compressionat at sites of articulation. It is also found at epiphyseal growth plates.

===Elastic Cartilage===

===Elastic Cartilage===

Elastic cartilage has a yellow appearance and is found in auricular cartilage, larynx, eustacian tube, and epiglottis. It is surrounded by perichondrium and has resiliance with added flexibility.

Elastic cartilage has a yellow appearance and is found in auricular cartilage, larynx, eustachian tube, and epiglottis. It is surrounded by perichondrium and has resiliance with added flexibility.

===Fibrocartilage===

===Fibrocartilage===

Fibrocartilage has more collagen ('''Type I''') and less proteglycans than hyaline. It resists high tensional strain and is often in transition with hyaline. It is found in intervertebral discs, tendon/ligament attachment to bone, joint menisci, and articular surface of some joints (such as the temperomandibular). It has NO perichondrium.

Fibrocartilage has more collagen ('''Type I''') and less proteoglycans than hyaline. It resists high tensional strain and is often in transition with hyaline. It is found in intervertebral discs, tendon/ligament attachment to bone, joint menisci, and articular surface of some joints (such as the temporomandibular). It has NO perichondrium.

[[Category:Bone and Cartilage - Anatomy & Physiology]]

[[Category:Bone and Cartilage - Anatomy & Physiology]][[Category:A&P Done]]