Changes

===Pigmentation===

===Pigmentation===

*[[Pigmentation and Calcification - Pathology#Lipofuscin|'''Lipofuscin''']]

*[[Pigmentation - Pathology#Lipofuscin|'''Lipofuscin''']]

**Wear and tear pigment accumulating in secondary lisosomes -> converted into compact residual bodies

**Wear and tear pigment accumulating in secondary lisosomes -> converted into compact residual bodies

**Due to old age, past or recent cachexia or starvation

**Due to old age, past or recent cachexia or starvation

**Histologically:

**Histologically:

***Rounded yellow to brown granules at both poles of nucleus of the skeletal myofiber

***Rounded yellow to brown granules at both poles of nucleus of the skeletal myofiber

*[[Pigmentation and Calcification - Pathology#Melanin|'''Melanin''']]

*[[Pigmentation - Pathology#Melanin|'''Melanin''']]

**As part of congenital melanosis of calves in fascial sheaths and epimysium

**As part of congenital melanosis of calves in fascial sheaths and epimysium

**Grossly - black foci

**Grossly - black foci