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Created page with "* Copper deficiency in the pregnant ewe can result in "''swayback'''" in lambs. ** Due to white matter degeneration in the central nervous system of prenatal and neonatal lambs. ..."
* Copper deficiency in the pregnant ewe can result in "''swayback'''" in lambs.
** Due to white matter degeneration in the central nervous system of prenatal and neonatal lambs.
* The degeneration is thought to be a mixture of both hypomyelination and demyelination.
* The central nervous system of the lambs is affected.
** Neonatal lambs show an ataxia in the first few weeks of life.
*** Due to demyelination of dorsolateral and ventromedial tracts in the white matter of the spinal cord.
** More severe lesions can be present in lambs affected prenatally.
*** Destruction of subcortical white matter in the brain.
**** The extent of this varies.
* It is unknown how copper deficiency exerts this effect.
** Supplementation in pregnancy prevents the prenatal form.
** Supplementation in the first few weeks will alleviate the neonatal form.


[[Category:Neurological Diseases - Sheep]]
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