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Created page with "Tumours within the pituitary fossa may be functional and sectrete trophic factors. However, more commonly they are non-functional and are space-occupying lesions. Pressure on ne..."
Tumours within the pituitary fossa may be functional and sectrete trophic factors. However, more commonly they are non-functional and are space-occupying lesions.
Pressure on neighbouring structures causes clinical signs, for example:
*Pressure on the optic chiasma produces ocular signs.
*Pressure on the hypothalamus may lead to [[Frohlich's Adiposogenital Syndrome - Pathology|Frohlich's adiposogenital syndrome]].
*Pressure on the neurohyposphysis may lead to failure of ADH secretion. This will allow large volumes of water to be lost form the kidney; [[Diabetes Insipidus]].
[[Image:Pituitary tumour.jpg|right|thumb|125px|<small><center>'''Pituitary neoplasia'''. Courtesy of A. Jefferies</center></small>]]
Neoplasia may be derived from:
*Pituitary itself.
*Surrounding brain tissue.
*Ependyma.
====Pituitary neoplasia in the horse====
Neoplasia usually occurs in the ''pars intermedia'' of the anterior pituitary and compresses the hypothalamus.
''Clinical signs'':
*Polyuria and polydipsia.
*Increased appetite reulting in increased food intake and downregulation of insulin receptors. This leads to a hyperglycaemia.
*Somnolence.
*Muscle wekaness.
*Hirsutism.
*Hyperhidrosis.
[[Category:Pituitary Gland - Pathology]]
[[Category:Neoplasia]]
Pressure on neighbouring structures causes clinical signs, for example:
*Pressure on the optic chiasma produces ocular signs.
*Pressure on the hypothalamus may lead to [[Frohlich's Adiposogenital Syndrome - Pathology|Frohlich's adiposogenital syndrome]].
*Pressure on the neurohyposphysis may lead to failure of ADH secretion. This will allow large volumes of water to be lost form the kidney; [[Diabetes Insipidus]].
[[Image:Pituitary tumour.jpg|right|thumb|125px|<small><center>'''Pituitary neoplasia'''. Courtesy of A. Jefferies</center></small>]]
Neoplasia may be derived from:
*Pituitary itself.
*Surrounding brain tissue.
*Ependyma.
====Pituitary neoplasia in the horse====
Neoplasia usually occurs in the ''pars intermedia'' of the anterior pituitary and compresses the hypothalamus.
''Clinical signs'':
*Polyuria and polydipsia.
*Increased appetite reulting in increased food intake and downregulation of insulin receptors. This leads to a hyperglycaemia.
*Somnolence.
*Muscle wekaness.
*Hirsutism.
*Hyperhidrosis.
[[Category:Pituitary Gland - Pathology]]
[[Category:Neoplasia]]