Changes

The endocrine system typically has effects on the hair growth cycle so alopecia is a common finding.  Many types of endocrine skin disease cause similar pathology.   

The endocrine system typically has effects on the hair growth cycle so alopecia is a common finding.  Many types of endocrine skin disease cause similar pathology.   

Affects dogs more than any other species.

Affects dogs more than any other species.

===Specific changes associated with disease===

===Specific changes associated with disease===

====[[Thyroid Gland - Pathology#Hypothyroidism|'''Hypothyroidism''']]====

====[[Hypothyroidism|'''Hypothyroidism''']]====

*Grossly: endocrine alopecia mainly over trunk and neck

*Grossly: endocrine alopecia mainly over trunk and neck

*Microscopically: endocrine alopecia plus mucin within the dermis -> myxoedema (dermal thickening), acanthotic epidermal and follicular infundibular epithelium

*Microscopically: endocrine alopecia plus mucin within the dermis -> myxoedema (dermal thickening), acanthotic epidermal and follicular infundibular epithelium

*Secondary pyoderma is common

*Secondary pyoderma is common

====[[Adrenal Glands - Pathology#Adrenal_Hyperfunction|'''Hyperadrenocorticism''']]====

====[[Hyperadrenocorticism|'''Hyperadrenocorticism''']]====

*Grossly: endocrine alopecia except on head and extremities, thin skin, comedones, easy bruising and poor wound healing, sometimes involves [[Adrenal Glands - Pathology#Pathophysiology_2|calcinosis cutis]]  

*Grossly: endocrine alopecia except on head and extremities, thin skin, comedones, easy bruising and poor wound healing, sometimes involves [[Adrenal Glands - Pathology#Pathophysiology_2|calcinosis cutis]]  

**In cats, skin is very easily torn

**In cats, skin is very easily torn