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Skin Environmental - Pathology (view source)

Revision as of 16:00, 21 February 2011

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|linkpage =Integumentary System - Pathology
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|linktext =Integumentary System
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|maplink = Integumentary System (Content Map) - Pathology
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==Chemical damage==
 
==Chemical damage==
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===Contact dermatitis===
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===Contact Dermatitis===
 
*Results due to exposure to chemicals (not immunologic reaction)
 
*Results due to exposure to chemicals (not immunologic reaction)
 
**Acids, alkali, detergents, irritant plants ''etc.''
 
**Acids, alkali, detergents, irritant plants ''etc.''
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**Superficial perivascular inflammation
 
**Superficial perivascular inflammation
 
**Necrosis may be caused by corrosive substances
 
**Necrosis may be caused by corrosive substances
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[[Category:Integumentary System - Chemical Damage]]
 
===Ergot poisoning===
 
===Ergot poisoning===
 
*Caused by ingestion of grains or grass contaminated by fungus ''Claviceps purpurae''
 
*Caused by ingestion of grains or grass contaminated by fungus ''Claviceps purpurae''
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**Red and swollen extremities
 
**Red and swollen extremities
 
**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] may develop on pinnae and tail
 
**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] may develop on pinnae and tail
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[[Category:Integumentary System - Chemical Damage]]
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===Fescue poisoning===
 
===Fescue poisoning===
 
*Caused by excessive consumption of ''Festuca arudinacea''
 
*Caused by excessive consumption of ''Festuca arudinacea''
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**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] of extremities
 
**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] of extremities
 
**Similar to [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]]
 
**Similar to [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]]
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[[Category:Integumentary System - Chemical Damage]]
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===Selenium poisoning===
 
===Selenium poisoning===
 
*Caused by ingestion of plants that have accummulated excessive amounts of selenium
 
*Caused by ingestion of plants that have accummulated excessive amounts of selenium
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**Poor hair quality, partial alopecia
 
**Poor hair quality, partial alopecia
 
**Horses - loss of mane and tail hair, deformed hooves that may be shed
 
**Horses - loss of mane and tail hair, deformed hooves that may be shed
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[[Category:Integumentary System - Chemical Damage]]
    
==Physical damage==
 
==Physical damage==
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**Perivascular and periadnexal plasma cell accumulation
 
**Perivascular and periadnexal plasma cell accumulation
 
**May be associated with mild snsory polyneuropathy
 
**May be associated with mild snsory polyneuropathy
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[[Category:Integumentary System - Physical Damage]]
    
===Callus===
 
===Callus===
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**[[Skin Glossary - Pathology|Comedones]] and follicular cysts may be present, potentially rupture and cause secondary pyoderma  
 
**[[Skin Glossary - Pathology|Comedones]] and follicular cysts may be present, potentially rupture and cause secondary pyoderma  
 
**Excessive keratin widening follicular openings
 
**Excessive keratin widening follicular openings
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[[Category:Integumentary System - Physical Damage]]
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===Feline psychogenic alopecia===
 
===Feline psychogenic alopecia===
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**Usually normal skin
 
**Usually normal skin
 
**Possibly increased [[Skin Glossary - Pathology|telogen]] follicles
 
**Possibly increased [[Skin Glossary - Pathology|telogen]] follicles
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[[Category:Integumentary System - Physical Damage]]
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===Injection site reaction===
 
===Injection site reaction===
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*Cats may develop fibrosarcomas secondary to vaccination
 
*Cats may develop fibrosarcomas secondary to vaccination
 
*Dogs, especially poodles, may develop lymphoplasmacytic panniculitis and perivasculitis, vasculitis and follicular atrophy secondary to killed rabies vaccine
 
*Dogs, especially poodles, may develop lymphoplasmacytic panniculitis and perivasculitis, vasculitis and follicular atrophy secondary to killed rabies vaccine
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[[Category:Integumentary System - Physical Damage]]
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===Intertrigo===
 
===Intertrigo===
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*Cows with large, pendolous udder may become affected in area between thigh and udder
 
*Cows with large, pendolous udder may become affected in area between thigh and udder
 
**In severe cases, skin and subcutis may slough
 
**In severe cases, skin and subcutis may slough
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[[Category:Integumentary System - Physical Damage]]
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===Pyotraumatic dermatitis===
 
===Pyotraumatic dermatitis===
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**Superficial erosive to ulcerative exudative dermatitis
 
**Superficial erosive to ulcerative exudative dermatitis
 
**May be deeper suppurative folliculitis
 
**May be deeper suppurative folliculitis
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[[Category:Integumentary System - Physical Damage]]
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===Radiation damage===
 
===Radiation damage===
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**Ulceration
 
**Ulceration
 
**In severe damage, squamous cell carcinoma may develop
 
**In severe damage, squamous cell carcinoma may develop
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[[Category:Integumentary System - Physical Damage]]
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===Low temperature damage===
 
===Low temperature damage===
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*Areas affected are extremities
 
*Areas affected are extremities
 
*Lesions consist of [[Necrosis - Pathology#Gangrene|gangrene]] and necrotic tissue
 
*Lesions consist of [[Necrosis - Pathology#Gangrene|gangrene]] and necrotic tissue
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[[Category:Integumentary System - Physical Damage]]
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===High temperature damage===
 
===High temperature damage===
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***Degenerated subepidermal collagen
 
***Degenerated subepidermal collagen
 
***May involve large numbers of [[Neutrophils|neutrophils]] if secondary ifection is present
 
***May involve large numbers of [[Neutrophils|neutrophils]] if secondary ifection is present
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[[Category:Integumentary System - Physical Damage]]
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==Sunlight damage==
 
==Sunlight damage==
 
*Transient erythema may develop into sunburn erythema (warmth, swelling, pain)
 
*Transient erythema may develop into sunburn erythema (warmth, swelling, pain)
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*Melanogenesis
 
*Melanogenesis
 
*Immune responses of skin are reduced by UV light
 
*Immune responses of skin are reduced by UV light
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[[Category:Integumentary System - Sunlight Damage]]
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===Solar dermatosis and neoplasia===
 
===Solar dermatosis and neoplasia===
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*If damage repaired prior to mitosis - no lasting effect
 
*If damage repaired prior to mitosis - no lasting effect
 
*If mitosis occurs before repair, post-mitotic repair is prone to faults and DNA mutations may result in neoplasia
 
*If mitosis occurs before repair, post-mitotic repair is prone to faults and DNA mutations may result in neoplasia
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[[Category:Integumentary System - Sunlight Damage]]
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===Solar dermatitis===
 
===Solar dermatitis===
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**Dermal fibrosis
 
**Dermal fibrosis
 
**Dogs may develop actinic [[Skin Glossary - Pathology|comedones]]
 
**Dogs may develop actinic [[Skin Glossary - Pathology|comedones]]
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[[Category:Integumentary System - Sunlight Damage]]
    
===[[Photosensitisation]]===
 
===[[Photosensitisation]]===
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**Vasculitis of superficial dermal vessels
 
**Vasculitis of superficial dermal vessels
 
**Thrombi may be seen
 
**Thrombi may be seen
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[[Category:Integumentary System - Sunlight Damage]]
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