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| − | ===Injection site reaction=== | + | ===[[Injection Site Reaction]]=== |
| − | *May be caused by subcutaneous injections
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| − | *Granulomatous nodules form with central necrotic and foreign material
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| − | *Macrophages and multinucleated giant cells around the centre
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| − | *Surrounded by granulation tissue, perivascular lymphocytes that may form lymphoid follicles, eosinophils
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| − | *Cats may develop fibrosarcomas secondary to vaccination
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| − | *Dogs, especially poodles, may develop lymphoplasmacytic panniculitis and perivasculitis, vasculitis and follicular atrophy secondary to killed rabies vaccine
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| − | [[Category:Integumentary System - Physical Damage]]
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