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Type I Hypersensitivity (view source)
Revision as of 16:17, 22 February 2011
, 16:17, 22 February 2011no edit summary
* [[Flea Allergic Dermatitis|Flea allergic dermatitis]]
* [[Flea Allergic Dermatitis|Flea allergic dermatitis]]
* [[Culicoides Hypersensitivity|Sweet itch]]
* [[Culicoides Hypersensitivity|Sweet itch]]
==From Pathology==
*Mediated by pharmacologically active substances from [[Mast Cells|mast cells]] and [[Basophils|basophils]]
**Due to antigen-antibody (usually [[IgE]]) binding to receptors on those cells
*Substances include histamine, serotonin, leukotriens, prostaglandins
*Can be systemic or local
*Skin becomes pruritic, raised erythematous borders of wheals
*Immediate reaction
*Includes:
**[[Skin Immunologic - Pathology#Atopy|Atopic dermatitis]]
**[[Skin Glossary - Pathology|Urticaria]]
**Angioedema
**Fly bite hypersensitivity
**Gastrointestinal parasites
**Food
*Microscopically:
**Capillary dilation, oedema, mast cell degranulation, eosinophil infiltration
[[Category:Hypersensitivity]]
[[Category:Hypersensitivity]]