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Bullous Pemphigoid
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Revision as of 16:51, 22 February 2011
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16:51, 22 February 2011
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'''Pathogenesis:''' [[Type II Hypersensitivity|Type II hypersensitivity]]?
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'''Pathogenesis
:
'''
[[
Type II Hypersensitivity
|
Type II hypersensitivity
]]
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*Dogs and horses
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*Involves oral cavity, mucocutaneous junctions, groin and axilla
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*Subepidermal vesicles and bullae
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*Antibodies bound to basement membrane
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*Grossly
:
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**Similar to
[[
Pemphigus
|
Pemphigus vulgaris
]]
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*Microscopically:
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**Bullae containing fibrin, [[Neutrophils|neutrophils]] or [[Eosinophils|eosinophils]]
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**Basement membrane forms floor of bullae and roof is lined with basal cells
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*Bullae may rupture -> ulcers
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[[Category:Integumentary System - Autoimmune Reactions]]
[[Category:Antibody Mediated Autoimmune Diseases]]
[[Category:Antibody Mediated Autoimmune Diseases]]
[[Category:To Do - Blood]][[Category:To Do - Clinical]]
[[Category:To Do - Blood]][[Category:To Do - Clinical]]
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