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Canine Dermatomyositis (view source)
Revision as of 16:53, 22 February 2011
, 16:53, 22 February 2011no edit summary
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*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
*Lesions - vesiculating dermatitis
*Lesions - vesiculating dermatitis
**Face, lips, external ears, later distal extremities
**Face, lips, external ears, later distal extremities
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
+
+*Hereditary in Collies and Shetland sheepdgs
+*Lesions resemble [[Muscles Inflammatory - Pathology#Canine polymyositis|canine polymyositis]]
+*Also degeneration of blood vessels -> muscle [[Muscles Degenerative - Pathology#Ischaemia|microinfarcts]]
+*Usually generalised but temporalis and other masticatory muscles may be involved the most
+*Microscopically: inclusion bodies in endothelial cells
+*Best place for biopsy is anterior and most superficial temporalis muscle
+*Also involves skin, may involve the oesophagus
+
[[Category:Integumentary System - Autoimmune Reactions]]
[[Category:Integumentary System - Autoimmune Reactions]]