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Bones Developmental - Pathology (view source)
Revision as of 17:26, 27 February 2011
, 17:26, 27 February 2011no edit summary
***Fine bones, poor musculature, small heads, scoliosis
***Fine bones, poor musculature, small heads, scoliosis
**Histologically:
**Histologically:
***Abnormal centres of [[Bones - normal#Bone development|endochondral ossification]]
***Abnormal centres of [[Bone & Cartilage Development - Anatomy & Physiology|endochondral ossification]]
***Nodular cartilage hypertrophy
***Nodular cartilage hypertrophy
*Occurs in sheep, dogs, cattle, horses
*Occurs in sheep, dogs, cattle, horses
*Failure of resorption by osteoclasts -> failure of remodelling of [[Bones - normal#Bone organisation|cancellous bone]]
*Failure of resorption by osteoclasts -> failure of remodelling of [[Bones - Anatomy & Physiology#Organisation of Bone|cancellous bone]]
*Bones become thickened and dense but brittle
*Bones become thickened and dense but brittle
*Marrow cavites are full of unresorbed primary spongiosa
*Marrow cavites are full of unresorbed primary spongiosa
*Usually resolves spontaneously in one to two weeks of life
*Usually resolves spontaneously in one to two weeks of life
*More severe cases exceding compensatory capabilities will persisist
*More severe cases exceding compensatory capabilities will persisist
*[[Bones - normal#Bone development|Cartilage development]] is affected
*[[Bone & Cartilage Development - Anatomy & Physiology|Cartilage development]] is affected
*Often associated with [[Bones Developmental - Pathology#Angular limb deformity|angular limb deformity]]
*Often associated with [[Bones Developmental - Pathology#Angular limb deformity|angular limb deformity]]
*Also called '''epiphysitis''' and '''physeal dysplasia'''
*Also called '''epiphysitis''' and '''physeal dysplasia'''
*Problem of [[Bones - normal#Bone development|endochondral ossification]]
*Problem of [[Bone & Cartilage Development - Anatomy & Physiology|endochondral ossification]]
*Two age groups
*Two age groups
**Weanlings
**Weanlings