Changes

**Histologically:

**Histologically:

***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]

***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]

***Middle zone - [[Bones - normal#Normal structure|osteoblasts]] depositing osteoid and bone

***Middle zone - [[Bones - Anatomy & Physiology|osteoblasts]] depositing osteoid and bone

***Outer zone - [[Bones - normal#Bone organisation|trabecular bone]] remodelled by [[Bones - normal#Normal structure|osteoclasts]]

***Outer zone - [[Bones - Anatomy & Physiology|trabecular bone]] remodelled by [[Bones - Anatomy & Physiology|osteoclasts]]

*'''Progressive''' (fibrodysplasia ossificans progressiva)

*'''Progressive''' (fibrodysplasia ossificans progressiva)

**In connective tissue associated with skeletal muscle

**In connective tissue associated with skeletal muscle