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Bones Developmental - Pathology (view source)

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===Osteopetrosis ~~(Marble bone disease)~~===

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===[[Osteopetrosis]] ===

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*Occurs in sheep, dogs, cattle, horses

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*Failure of resorption by osteoclasts -> failure of remodelling of [[Bones - Anatomy & Physiology#Organisation of Bone|cancellous bone]]

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*Bones become thickened and dense but brittle

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*Marrow cavites are full of unresorbed primary spongiosa

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*Thickened intramembranous bones of skull -> altered shape of brain

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*Associated with severe viral infections, e.g. '''FeLV''', [[Bovine Viral Diarrhoea Virus|BVD]]

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*Hereditary in Angus cattle

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~~[[Category:Bones - Developmental Pathology]]~~

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