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Ferrets (Laboratory) - Pathology (view source)
Revision as of 17:32, 2 March 2011
, 17:32, 2 March 2011→General GI
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Gross lesions are not normally associated with IBD, aside from generally inflammed GI tract lining. Microscopic lesions will include small to moderate numbers of lymphocytes, plasma cells and eosinophils, mainly within the small intestine. Lymphocytic forms of IBD are associated with intramucosal lymphocytes and villi atrophy, blunting and fusion. Microscopic lesions associated with the eosinophilic form include eosinophilic infiltrates within the small intestine. Additionally, prominent eosinophilic infiltrates may be seen in the mesenteric lymph nodes, liver, pancreas or other abdominal organs.
Gross lesions are not normally associated with IBD, aside from generally inflammed GI tract lining. Microscopic lesions will include small to moderate numbers of lymphocytes, plasma cells and eosinophils, mainly within the small intestine. Lymphocytic forms of IBD are associated with intramucosal lymphocytes and villi atrophy, blunting and fusion. Microscopic lesions associated with the eosinophilic form include eosinophilic infiltrates within the small intestine. Additionally, prominent eosinophilic infiltrates may be seen in the mesenteric lymph nodes, liver, pancreas or other abdominal organs.
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'''GI Foreign Bodies'''
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Foreign bodies are commonly seen in young or bored, cage-bound ferrets. They will commonly ingest latex, plastic, foam rubber, towels or other forms of bedding. Anorexia and passage of abnormal stools are common clinical signs.
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Gross lesions will include a focal area of abdominal distention with or without haemorrhage. The wall of the intestines at the site of blockage may be thinner than that of the adjacent intestine due to continuous peristaltic movements at the site of blockage. In rare cases, intestinal perforation may be seen. Microscopic lesions may include ulceration, necrosis and thinning of the muscular layers at the site of blockage. In longstanding blockages there will be marked attenuation of villi and granulation tissue.
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