This finding is extremely common in ferrets, although the causes are unknown. It is most common in middle to old age ferrets but has been reported in animals from six months old. The incidence of neoplasia in splenomegally is less than 10%. However, marked enlargement of the spleen increases the spleen's phagocytic capability resulting in increased RBC breakdown. In chronic cases, anemia may occur. | This finding is extremely common in ferrets, although the causes are unknown. It is most common in middle to old age ferrets but has been reported in animals from six months old. The incidence of neoplasia in splenomegally is less than 10%. However, marked enlargement of the spleen increases the spleen's phagocytic capability resulting in increased RBC breakdown. In chronic cases, anemia may occur. |