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Ferrets (Laboratory) - Pathology (view source)
Revision as of 21:52, 2 March 2011
, 21:52, 2 March 2011→Urinary System
'''Prostatic Squamous Metaplasia'''
'''Prostatic Squamous Metaplasia'''
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Squamous metaplasia of the prostate has only recently been recognised as a common cause of dysuria and urethral blockage in ferrets. The squamous change within the prostate is due to excess estrogens caused by proliferative adrenal lesions (see endocrine section). Accumulation of secretory material and lamellated keratin results in the formation of porstatic cysts. The impingement of these cysts upon the prostatic urethra results in dysuria and in some cases complete blockage. Surgery is commonly required.
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Gross lesions include single to multiple fluctant cysts present near the bladder trigone. Cysts will be thick-walled and firm. Concurrent confirmation of enlarged adrenal glands or adrenal neoplasm is often possible. Microscopic lesions will include atrophic prostate glands around the periphery of the cysts. Cyst walls will consist of multiple layers of squamous epithelium surrounded by variable levels of fibrous connective tissue. The luminal contents of the cysts can contain material ranging from keratin debris to purulent inflammatory material.
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===Diabetes===
===Diabetes===