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Bones Degenerative - Pathology (view source)

Revision as of 11:56, 3 March 2011

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===Osteoporosis (Atrophy)===
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===[[Osteoporosis]] (Atrophy)===
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*Lesion, not a disease
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*Reduction in bone mass due to reduced osteoid (bone atrophy)
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*Bone resorption exceeds formation -> pathological loss of bone
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*Resorbed from:
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**Trabeculae, preserving the weight bearing ones until last
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**Endosteal surface of cortical bone
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**Along vascular channels
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*Longitudinal section
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**Fewer thin trabeculae
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**Enlarged medulla
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**Thin, porous cortex
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*Bone which remains is normally mineralised
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*Can be localised or generalised*Caused by:
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**Starvation - in farm animals due to protein and energy deficiency
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**Nutritional deficiency (calcium) and hypocalcaemia -> bone resorption
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**Senility
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***Physiological loss of skeletal mass with age
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***May be excessive in some individuals
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***Histologically - dead [[Bones - Anatomy & Physiology|osteocytes and empty lacunea]]
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**Physical inactivity (disuse) - muscular inactivity and reduced weight bearing, e.g. during limb casting
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**Glucocorticoids
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**[[:Category:Enteritis, Parasitic|Intestinal parasitism]] - in ruminants, malabsorption due to severe infestation
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**[[Congenital and Neonatal Disease - Pathology#Copper Deficiency|Copper deficiency]] - in lambs, calves, foals, pigs and dogs -> brittle bones
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*May be reversed in young growing animals
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===Osteosis===
 
===Osteosis===
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*Associated with [[Joints Degenerative - Pathology#Calve Legg-Perthe's disease|Calve-Legg Perthe's disease]]
 
*Associated with [[Joints Degenerative - Pathology#Calve Legg-Perthe's disease|Calve-Legg Perthe's disease]]
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[[Category:Bones - Degenerative Pathology]]
 
===Bone cysts===
 
===Bone cysts===
 
[[Image:Bone cysts dog.jpg|right|thumb|100px|<small><center>Bone cysts (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Bone cysts dog.jpg|right|thumb|100px|<small><center>Bone cysts (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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*Radiography is essential to help differentiate with cavity of a neoplasm
 
*Radiography is essential to help differentiate with cavity of a neoplasm
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[[Category:Bones - Degenerative Pathology]]
 
===Calcium hydroxylapatite deposition disease===
 
===Calcium hydroxylapatite deposition disease===
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*[[More on Calcium hydroxylapatite deposition disease|More about Calcium hydroxylapatite deposition disease]]
 
*[[More on Calcium hydroxylapatite deposition disease|More about Calcium hydroxylapatite deposition disease]]
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[[Category:Bones - Degenerative Pathology]]
 
===Physeal dysplasia with slipped capital femoral epiphysis===
 
===Physeal dysplasia with slipped capital femoral epiphysis===
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*[[More about Physeal dysplasia]]
 
*[[More about Physeal dysplasia]]
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[[Category:Bones - Degenerative Pathology]]
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[[Category:Musculoskeletal System - Pathology]]
 
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