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Line 1: |
| − |
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| | *No causative agent has been found | | *No causative agent has been found |
| | *Seem to be immune-mediated diseases | | *Seem to be immune-mediated diseases |
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Line 5: |
| | ===Erosive=== | | ===Erosive=== |
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| − | ====Rheumatoid arthritis==== | + | ====[[Rheumatoid Arthritis]]==== |
| − | *Occurs in the dog, mainly smaller breeds
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| − | *Uncommon
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| − | *Progressive erosive polyarthritis
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| − | *Mostly involves elbows, stifles, carpal and tarsal joints
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| − | *Grossly:
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| − | **Marked villus hypertrophy of synovial membrane
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| − | **Cartilage erosion
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| − | **[[Musculoskeletal Terminology - Pathology|Pannus and periarticular osteophyte]] formation
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| − | **In severe cases ankylosis
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| − | *Histologically:
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| − | **Hyperplasia of lining cells
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| − | **Proliferative synovitis
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| − | **Synovial membrane has fibrin deposits
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| − | **Lymphoid and plasma cell infiltration
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| − | **Surrounding haemorrhagic areas
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| − | **Macrophages containing [[Pigmentation - Pathology#Haemosiderin|haemosiderin]]
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| − | **Connective tissue may contain foci of necrosis
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| − | **Areas of erosion of peripheral articular cartilage and underlying subchondral bone
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| − | *Pathogenesis:
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| − | **May involve deposition of immune complexes within joints
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| − | **Substances degrading cartilage are released by synovial cells and macrophages involved in pannus formation
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