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Created page with "*Metaplasia of muscle to bone *'''Localised''' **Only in single muscle or a single group of muscles **May be associated with trauma **Seen in horses and dogs **Histologically: *..."
*Metaplasia of muscle to bone
*'''Localised'''
**Only in single muscle or a single group of muscles
**May be associated with trauma
**Seen in horses and dogs
**Histologically:
***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]
***Middle zone - [[Bones - Anatomy & Physiology|osteoblasts]] depositing osteoid and bone
***Outer zone - [[Bones - Anatomy & Physiology|trabecular bone]] remodelled by [[Bones - Anatomy & Physiology|osteoclasts]]
*'''Progressive''' (fibrodysplasia ossificans progressiva)
**In connective tissue associated with skeletal muscle
**Secondary involvement of muscle tissue
**In pigs and cats
**Histologically:
***Bundles of dense fibrous connective tissue
***May contain accumulations of cartilage, bone or calcium
**Hyperplastic connective tissue -> compression of adjacent skeletal muscle -> [[Muscles Degenerative - Pathology#Atrophy|atrophy]]
[[Category:Muscles - Degenerative Pathology]]
*'''Localised'''
**Only in single muscle or a single group of muscles
**May be associated with trauma
**Seen in horses and dogs
**Histologically:
***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]
***Middle zone - [[Bones - Anatomy & Physiology|osteoblasts]] depositing osteoid and bone
***Outer zone - [[Bones - Anatomy & Physiology|trabecular bone]] remodelled by [[Bones - Anatomy & Physiology|osteoclasts]]
*'''Progressive''' (fibrodysplasia ossificans progressiva)
**In connective tissue associated with skeletal muscle
**Secondary involvement of muscle tissue
**In pigs and cats
**Histologically:
***Bundles of dense fibrous connective tissue
***May contain accumulations of cartilage, bone or calcium
**Hyperplastic connective tissue -> compression of adjacent skeletal muscle -> [[Muscles Degenerative - Pathology#Atrophy|atrophy]]
[[Category:Muscles - Degenerative Pathology]]