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| − | ===Equine rhabdomyolysis=== | + | ===[[Equine Rhabdomyolysis]]=== |
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| − | *'''Azoturia''' (Monday morning disease)
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| − | **Acute
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| − | **Due to exercise following a prolonged period of rest
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| − | **Clincal signs:
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| − | ***Unable to move
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| − | ***Sweating
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| − | ***Tremors
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| − | ***Swollen and hard lumbar, gluteal and femoral muscles
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| − | **Myoglobin leaks from muscle cells -> leaks into urine -> urine is dark red/brown (myoglobinuria) -> damages renal tubules
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| − | **Grossly:
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| − | ***Salmon pink muscles -> dark, moist, swollen +/- pale streaks
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| − | **Histologically:
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| − | ***Segmental myofibre [[Muscles Degenerative - Pathology#Necrosis|necrosis]]
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| − | ****Multifocal and monophasic, but may be multiphasic if repeated bouts
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| − | ***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
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| − | ***Minor inflammatory reaction and calcification
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| − | *'''Tying-up'''
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| − | **Similar to azoturia but much milder
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| − | **Grossly - normal muscle
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| − | **Histologically - same as azoturia
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| − |
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| − | [[Category:Muscles - Degenerative Pathology]]
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| | ===[[Porcine Stress Syndrome]]=== | | ===[[Porcine Stress Syndrome]]=== |
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| | ==Neuromuscular junction diseases== | | ==Neuromuscular junction diseases== |