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Created page with "===Primary neoplasia=== *Rare in domestic animals *'''Rhabdomyoma''' **Benign **''E.g.'' laryngeal in dogs **Grossly: ***Lobulated with no capsule **Histologically: ***Large gra..."
===Primary neoplasia===
*Rare in domestic animals
*'''Rhabdomyoma'''
**Benign
**''E.g.'' laryngeal in dogs
**Grossly:
***Lobulated with no capsule
**Histologically:
***Large granular cells
***Positive staining for myoglobin and desmin (immunoperoxidase technique)
***Z - band material can be seen by electron microscopy
*'''Rhabdomyosarcoma'''
**Malignant
**Mainly in dogs
**Metastases via lymphatics or venous routes -> in lymph nodes, lungs, spleen, heart and eleswhere in skeletal muscle
**Grossly:
***Pink masses with no capsule
**Histologically:
***Very varied
***Cells with or without visible cross striations
****Most easily seen with iron haematoxylin
****Muscle tissue only contains myoglobin detected by immunoperoxidase method
===Metastatic neoplasia===
*Can occur to skeletal muscle (e.g. carcinoma, haemangiosarcoma)
*'''Infiltrative lipomas''' of dogs
**Mature adipocyte tumours
**Usually deep in subcutis or muscle
**Infiltate along fascial planes or into muscles
**Grossly:
***Soft muscles
***Yellow fat separating fasciculi
**Histologically:
***Well-differentiated adipose cells
[[Category:Neoplasia]]
[[Category:Musculoskeletal System - Pathology]]
*Rare in domestic animals
*'''Rhabdomyoma'''
**Benign
**''E.g.'' laryngeal in dogs
**Grossly:
***Lobulated with no capsule
**Histologically:
***Large granular cells
***Positive staining for myoglobin and desmin (immunoperoxidase technique)
***Z - band material can be seen by electron microscopy
*'''Rhabdomyosarcoma'''
**Malignant
**Mainly in dogs
**Metastases via lymphatics or venous routes -> in lymph nodes, lungs, spleen, heart and eleswhere in skeletal muscle
**Grossly:
***Pink masses with no capsule
**Histologically:
***Very varied
***Cells with or without visible cross striations
****Most easily seen with iron haematoxylin
****Muscle tissue only contains myoglobin detected by immunoperoxidase method
===Metastatic neoplasia===
*Can occur to skeletal muscle (e.g. carcinoma, haemangiosarcoma)
*'''Infiltrative lipomas''' of dogs
**Mature adipocyte tumours
**Usually deep in subcutis or muscle
**Infiltate along fascial planes or into muscles
**Grossly:
***Soft muscles
***Yellow fat separating fasciculi
**Histologically:
***Well-differentiated adipose cells
[[Category:Neoplasia]]
[[Category:Musculoskeletal System - Pathology]]