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CNS Inflammation - Pathology (view source)

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===[[Granulomatous Meningoencephalitis]]===

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~~(GME)~~

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* An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]]

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* May occur as:

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** A disseminated disease

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** A focal mass lesion

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** A primary occular disease

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* Brainstem signs are common, although the forebrain is primarily affected.

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* May be incorrectly diagnosed as lymphoma.

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* Changes are apparent in the CSF.

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** There is usually a mononucloear pleocytosis.

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** Sometimes only protein is elveated.

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* Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.

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** However, biopsy is required for a definative diagnosis.

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* Life span is between 6 months and 1 year from diagnosis.

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~~====Treatment====~~

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[[Necrotising Meningoencephalitis]]

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* Immunosuppression:

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** Corticosteroids

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** Azathioprine

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** Cycophosphamide

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* Surgery

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** This is only appropriate if there is a focal mass.

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* Radiation therapy.

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~~[[Necrotising Meningoencephalitis]]~~

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~~[[:Category:CNS Non-Infectious Inflammatory Diseases]]~~

Bara

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CNS Inflammation - Pathology (view source)

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