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==Overview==
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== Introduction ==
Disease caused by the parasite [[Cryptosporidium|cryptosporidium]].
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This is a '''zoonotic''', diarrhoea- causing, disease of cattle and other domestic livestock caused by the parasite [[Cryptosporidium|cryptosporidium]].It is a protozoan parasite that inhabits crypt cells of the intestine. Transmission of the disease is faeco- oral. The disease is sever in humans and can be fatal in the immunocompromised. It causes severe sickness and diarrhoea for up to two weeks.<br>
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==Diagnosis==
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*Faecal smear
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== Clinical Signs ==
**Ziehl-Neelson (ZN) stain
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**Oocysts stain red against a blue/green background
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*Immunoassays
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Often seen in adolescent calves, may present as a sudden outbreak or as sporadic disease. Animals may have weight loss and and appear dull and depressed. Diarrhoea will be profuse and watery and may appear green/ black.
**Detect oocysts in faeces
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==Control==
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<br>
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*Isolate/quarantine bought-in calves
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== Diagnosis ==
**Treat if signs of [[Diarrhoea|diarrhoea]] present
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*Good hygiene, adequate bedding and disinfection of calf pens is important
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Clinical signs and age of cattle will provide a presumptive diagnosis. A faecal smear with&nbsp;'''Ziehl-Neelson''' (ZN) stain is diagnostic and if cryptosporidium is present then oocysts stain red against a blue/green background. Immunoassayscan also be performed to detect oocysts in faeces.
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*Prevention/treatment
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**Halofuginone
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***Halocur or Intervet
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***Oral dosage
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==Villus Atrophy in Enteritis==
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== Control ==
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* Affects calf, lamb, piglet, kitten.
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Isolate/quarantine bought-in calves maintain good hygiene by providing adequate bedding and disinfecting calf pens.  
* Increasingly important as part of the neonatal [[Diarrhoea|diarrhoea]] complex in calves.
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* Zoonosis.
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====Pathology====
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If diarrhoea is present and cryptosporidium has been detected then treat with halofuginon, trade names&nbsp;Halocur or Intervet. This treatment is given orally.
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=====Gross=====
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<br>
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* Intestines diffusely reddened, with fluid contents.
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[[Category:To_Do_-_Review]]
 
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=====Histological=====
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* Tiny parasites on surface of epithelium.
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* Villus atrophy and fusion.
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* Iinflammation (mainly lymphoid) in crypts and lamina propria.
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[[Category:To_Do_-_Clinical]]
 
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