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Also known as IPV
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== Introduction<br> ==
Caused by:[[Bovine Herpesvirus 1]]
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: venereal transfer
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This viral disease of cattle is also known as IPV Caused by [[Bovine Herpesvirus 1]]. Transmission of the disease is venereal and so the disease is now uncommon in cattle due to the constant use of artificial insemination (A.I.). The disease causes impaired reproductive performance and painful genital lesions on both cows and bulls. <br>
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====Pathogenesis====
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<br>
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*Painful genital lesions
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== Clinical Signs<br> ==
*Impaired reproductive performance
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*Frequent micturition
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====Diagnosis====
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Genital lesions and a pustular vagintis as the name suggests. On the male, lesions will be seen on the prepuce and sheath of the penis and in females there will be a pustular inflammatory process in the vagina, along with painful lesions here. In both sexes, freuent micturation is a common clinical sign. <br>
*Virus isolation and immunofluorescence
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====Control====
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<br>
*'''Vaccination''':
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**Two '''live attenuated''' vaccines are available in the UK, one is temperature-sensitive
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***Both given intranasally
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***Neither protect against re-infection when given during clinical outbreak, but can lessen the severity of the disease
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**'''Inactivated''' vaccines: intranasal/intramuscular administration
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***gE deletion makes this a '''marker vaccine'''
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***ELISA for gE deletion can enable culling of carrier animals
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*IPV has mostly been made obsolete by AI
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== Diagnosis ==
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[[Category:Reproductive Diseases - Cattle]]
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Virus isolation and immunofluorescence, with samples taken from swabs of the lesions.<br>
[[Category:To_Do_-_Clinical/Viruses]]
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<br>
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== Control ==
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'''Vaccination. '''There are two '''live attenuated''' vaccines are available in the UK, one is temperature-sensitive. Both are given intranasally, however, neither protect against re-infection when given during clinical outbreak, but can lessen the severity of the disease.&nbsp;'''Inactivated''' vaccines for intranasal/intramuscular administration have a&nbsp;gE deletion which makes this a '''marker vaccine.&nbsp;'''ELISA for gE deletion can enable culling of carrier animals.
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IPV has mostly been made obsolete by AI.
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<br>
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== References<br> ==
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Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) Bovine Medicine (Second edition), Blackwell Publishing<br>Bridger, J and Russell, P (2007) Virology Study Guide, Royal Veterinary College<br>Radostits, O.M, Arundel, J.H, and Gay, C.C. (2000) Veterinary Medicine: a textbook of the diseases of cattle, sheep, pigs, goats and horses Elsevier Health Sciences<br><br>
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<br>
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[[Category:Reproductive_Diseases_-_Cattle]] [[Category:To_Do_-_Review]]
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