− | '''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - Introduction|lymphocytes]] and [[B cell differentiation#Plasma cells|plasma cells]]. Bile duct hypertrophy and [[Liver Fibrosis|fibrosis]] are present. However, lymphocytic cholangitis does not progress to biliary [[Cirrhosis|cirrhosis]]. An immune-mediated aetiology has been postulated but this has not been substantiated to date. It is rarely associated with [[Pancreatitis - Dog and Cat|pancreatitis]], compared to [[Cholangitis, Neutrophilic]] | + | '''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - Introduction|lymphocytes]] and [[B cell differentiation#Plasma cells|plasma cells]]. Bile duct hypertrophy and [[Liver Fibrosis|fibrosis]] are present. However, lymphocytic cholangitis does not progress to biliary [[Cirrhosis|cirrhosis]]. An immune-mediated aetiology has been postulated but this has not been substantiated to date. It is rarely associated with [[Pancreatitis|pancreatitis]], compared to [[Cholangitis, Neutrophilic]] |