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Pathological changes depend on the direction of penetration; this is usually in an anterior-ventral direction. Pyogenic bacteria escape from the reticulum, causing localised [[Peritonitis|peritonitis]] and local fibrinous adhesions.
 
Pathological changes depend on the direction of penetration; this is usually in an anterior-ventral direction. Pyogenic bacteria escape from the reticulum, causing localised [[Peritonitis|peritonitis]] and local fibrinous adhesions.
Penetration of the [[Diaphragm - Anatomy & Physiology|diaphragm]] and [[Heart Structure - Anatomy & Physiology#Pericardium|pericardium]] results in [[Pericarditis|pericarditis]]. Penetration of the [[Heart - Anatomy & Physiology|heart]] itself results in [[Myocarditis|myocarditis]] and [[Endocarditis|endocarditis]]. Penetration of the [[Lungs - Anatomy & Physiology|lungs]] and pleura can occur resulting in pneumonia and pleurisy.
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Penetration of the [[Diaphragm - Anatomy & Physiology|diaphragm]] and [[Heart Structure - Anatomy & Physiology#Pericardium|pericardium]] results in [[Traumatic Pericarditis|pericarditis]]. Penetration of the [[Heart - Anatomy & Physiology|heart]] itself results in [[Myocarditis|myocarditis]] and [[Endocarditis|endocarditis]]. Penetration of the [[Lungs - Anatomy & Physiology|lungs]] and pleura can occur resulting in pneumonia and pleurisy.
 
Liver and splenic abscesses also occasionally occur following penetration of either organ.
 
Liver and splenic abscesses also occasionally occur following penetration of either organ.
  
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