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− | caused by [[Corynebacterium renale]]
| + | *Pyelonephritis is inflammation of the renal pelvis and parenchyma. |
| + | *Most often occurs in cows and sows. |
| + | *Main predisposing factor is urinary stasis which can occur due to pregnancy, following service in the sow, following uterine and bladder prolapse or the use of catheters in small animals. |
| + | *Usually occurs due to ascending bacterial infection from the lower urinary tract. |
| + | '''Gross pathology''' |
| + | *Kidney may be swollen with external patchy congestion. |
| + | *The medulla has streaks of inflammatory debris that extend into the cortex. |
| + | *The renal pelvis as well as the ureters are dilated and contain pus. |
| + | *In chronic cases, the kidney is shrunken, distorted and has gray patches among a diffuse, tan discolouration. The medulla has fibrous tracts that run into the capsule. |
| + | '''Histopathology''' |
| + | *Dilated tubules filled with [[Neutrophils|neutrophils]]. |
| + | *Presences of bacteria within the tubules. |
| + | *Necrosis of the pelvic epithelium and collecting tubules. |
| + | *In chronic cases, presence of fibrosis within the medulla as well as ascending fibrous tracts into the cortex. |
| + | '''Examples''' |
| + | *''[[Corynebacterium renale]]'' in cattle and ''Eubacterium suis'' in pigs. |
| + | '''Definitons''' |
| + | *''Pyelitis'' - infection involving the renal pelvis alone. |
| + | *''Pyonephritis'' - suppuration of the whole kidney. |
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| + | [[Category:Tubulointerstitial Disease]] |
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| + | [[Category:To Do - Urinary]] |