Changes

==Introduction==

==Introduction==

The major role of the gastrointestinal tract is the uptake of important electrolytes, nutrients and water and the excretion of some breakdown products. In cases of gastrointestinal disease, patients can often become dehydrated and in cases of malabsorptive disease, such things as hypoproteinaemia may develop. This has important implications for those patients requiring general anaesthesia as the patient is not only in a deteriorated state but things such as hypoproteinaemia and dehydration can alter the action of the drug due to these affecting protein binding and distribution for example. Weight loss is often a clincial sign in these patients, and so problems with temperature regulation may also be seen during anaesthestic procedures.

The major role of the gastrointestinal tract is the uptake of important electrolytes, nutrients and water and the excretion of some breakdown products. In cases of gastrointestinal disease, patients can often become dehydrated and in cases of malabsorptive disease, such things as hypoproteinaemia may develop. This has important implications for those patients requiring general anaesthesia as the patient is not only in a deteriorated state but things such as hypoproteinaemia and dehydration can alter the action of the drug due to these affecting protein binding and distribution for example. Weight loss is often a clincial sign in these patients, and so problems with temperature regulation may also be seen during anaesthestic procedures.

 

[[Category:Diseases and Anaesthesia]]

[[Category:Diseases and Anaesthesia]]