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[[Image:Equine Internal Medicine Q&A 17.jpg|centre|500px]]<br>

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'''A 12-year-old pony gelding is presented with a three week history of weight loss, inappetence, intermittent fever (up to 38.7°C) and ventral thoracic and abdominal oedema. Auscultation of the chest reveals bilateral absence of ventral lung sounds, and a pleural effusion is confirmed by ultrasonography. Thoracocentesis yields a large volume of blood-stained watery fluid. A tracheal wash did not reveal any any infectious cause.'''

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<FlashCard questions="2">
|q1=What is the most likely diagnosis?
|a1=Thoracic neoplasia. <br>
The commonest type of thoracic neoplasia in the horse is mediastinal lymphosarcoma.
|l1=
|q2=How can the diagnosis be confirmed?
|a2=
*Cytology of pleural fluid may reveal neoplastic cells.
*Similar fluid may be present in the peritoneal cavity.
*Neoplastic masses may be identifiable by thoracic radiography or ultrasonography.
*Mediastinal masses may sometimes extend through the thoracic inlet and be palpable externally at the base of the jugular groove; in this situation they may be amenable to biopsy.
*In the case of lymphosarcoma, peripheral lymph nodes may be enlarged due to neoplastic infiltration, and these may be biopsied.
|l2=

</FlashCard>

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