Changes

==Histology==

==Histology==

[[Image:Lobule Histology.jpg|thumb|right|250px|Liver Lobule Histology - Copyright RVC 2008]]

[[Image:Lobule Histology.jpg|thumb|right|250px|Liver Lobule Histology - from [[Gastrointestinal Tract Histology resource|GIT-2 tutorial]] ]]

The larger liver cells are called '''lobules'''. Each lobule contains an opening for the '''central vein''' and contains portal areas. The lobules are composed of liver cords called '''hepatocytes'''. Sinusoids are present between hepatocytes containing red blood cells. There is a connective tissue capsule around each liver lobule. A thin '''mesothelium''' covers the connective tissue layer.

The larger liver cells are called '''lobules'''. Each lobule contains an opening for the '''central vein''' and contains portal areas. The lobules are composed of liver cords called '''hepatocytes'''. Sinusoids are present between hepatocytes containing red blood cells. There is a connective tissue capsule around each liver lobule. A thin '''mesothelium''' covers the connective tissue layer.

The '''portal area''' present in the lobules contains the '''hepatic artery''', which has thick walls and a small diameter and the '''hepatic vein''', which has thin walls and a large and irregular shape. It also contains '''bile ducts''', with cuboidal or columnar epithelium and '''lymphatics''' that are small and delicate.

The '''portal area''' present in the lobules contains the '''hepatic artery''', which has thick walls and a small diameter and the '''hepatic vein''', which has thin walls and a large and irregular shape. It also contains '''bile ducts''', with cuboidal or columnar epithelium and '''lymphatics''' that are small and delicate.

[[Image:Portal Triad Histology.jpg|thumb|right|250px|Portal Triad Histology in a Lobule- Copyright RVC 2008]]

[[Image:Portal Triad Histology.jpg|thumb|right|250px|Portal Triad Histology in a Lobule- from [[Gastrointestinal Tract Histology resource|GIT-2 tutorial]] ]]

'''Hepatocytes''' are the smaller liver cells in the lobules. They contain glycogen granules and have a spherical nucleus. They form cords called '''branching plates''' (lamellae). The upper and lower margins are tight junctions. They have 3 functioning surfaces. '''Kupfer macrophages''' are present near the lining of the sinusoids. The hepatocytes tain pink as they are '''eosinophilic'''.

'''Hepatocytes''' are the smaller liver cells in the lobules. They contain glycogen granules and have a spherical nucleus. They form cords called '''branching plates''' (lamellae). The upper and lower margins are tight junctions. They have 3 functioning surfaces. '''Kupfer macrophages''' are present near the lining of the sinusoids. The hepatocytes tain pink as they are '''eosinophilic'''.