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− | [[Category:To Do - Steph]] | + | Also Known As — '''''Infectious coryza''''' — '''''Infectious Bronchitis''''' — '''''Infectious Proventriculitis''''' — '''''Avian Infectious Nephrosis''''' — '''''Avian Infectious Nephrosis''''' |
| + | Caused By — ''Avian Infectious Bronchitis Virus'' — ''AIBV'' — ''ICTV'' — ''IBV'' — ''AIB'' — ''IB'' |
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| + | ==Introduction== |
| + | Avian Infectious Bronchitis is a '''highly contagious''' viral disease primarily of the '''[[Respiratory System | respiratory system]]''' of birds, caused by a '''[[Coronaviridae | coronavirus]]'''. |
| + | The virus can also cause damage to the '''[[Kidney Anatomy and Physiology | kidneys]]''' and '''[[Oviduct - Anatomy & Physiology | oviducts]]'''. |
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| + | IBV is transmitted mainly by '''aerosols''' and also by contaminated people/vehicles/equipment. |
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| + | It can become '''latent''' in a bird and recrudesce with '''stress''', e.g. at point of lay. |
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| + | This disease is notifiable to the World Organisation for Animal Health [http://www.oie.int/ {OIE)] |
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| + | ==Signalment== |
| + | Chickens, pigeons and pheasants are affected. |
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| + | Disease is most severe in chicks. |
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| + | ==Distribution== |
| + | Worldwide |
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| + | ==Clinical Signs== |
| + | '''Reduced weight gain''' or '''egg production''' and reluctance to move is often the first indicator of disease. |
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| + | '''Mortality''' often occurs due to secondary infection, particularly due to ''E. coli'' and ''Mycoplasma'' infections. Mortality is highest in intensively reared broiler flocks. |
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| + | '''Sneezing, Coughing, Dyspnoea''', Ingesta present in respiratory passages, Nasal discharge, Abnormal lung sounds on auscultation |
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| + | '''Diarrhoea, dehydration''', polydipsia |
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| + | '''Polyuria, Pollakiuria''' |
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| + | Reluctance to move |
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| + | Swelling of the head and face |
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| + | Conjunctival congestion and increased lacrimation or ocular discharge |
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| + | '''Soft egg shells''', thin albumin and watery yolks |
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| + | Neurological signs |
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| + | ==Diagnosis== |
| + | In the acute phase, '''viral isolation''' can be attempted from eggs, tracheal swabs or tracheal/lung biopsies. |
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| + | If more than one week after initial infection, caecal tonsils or cloacal swabs are more reliable. |
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| + | '''RT-PCR''' can be performed on buccal or oropharyngeal swabs but will not differentiate live from dead virus isolate |
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| + | '''Agar Gel Precipitation''' and '''Immunofluorescent Antibody''' (IFAT) tests can also be used to detect virus. |
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| + | On '''post-mortem examination''', '''yellow catarrhal or caseous exudates''' are present in the trachea, nasal passages, sinuses and air sacs. |
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| + | On histopathology of the trachea, loss of cilia and sloughing with '''[[Heterophils | heterophilic infiltration]]''' is evident. |
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| + | The kidneys are '''pale and swollen''' and tubules distended with '''urates''' if nephritis is also present. Heterophilic inflammation and degeneration may be evident. |
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| + | Detection of '''viral antibodies''' is also valuable in surveillance, monitoring of vaccination and identification of latently infected birds. This can be performed using '''Agar Gel Immunodiffusion''' (AGID) , [[ELISA testing | ELISA]], Virus Neutralisation (VN) and Haemagglutination-Inhibition (HI). |
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| + | RT-PCR, VN and HI can also be used to type IBV isolates. |
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| + | ==Treatment== |
| + | '''No treatment''' is available for the viral infection. |
| + | Use of '''antibiotics''' in drinking water to treat and prevent secondary infection may reduce mortality and losses. |
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| + | ==Control== |
| + | '''Live and Killed IBV vaccines''' are available and widely used but cross-protection is poor and numerous serotypes exist so disease is not always prevented. Vaccinations can be administered as intra-muscular injections or sprays. Killed vaccines used alone do not induce immunity and therefore live vaccines are required to prime immunity first. |
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| + | Good biosecurity and hygiene protocols are imperative to control of this highly contagious disease. Particular efforts should be made with respect to '''ventilation''' and '''air quality'''. |
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| + | ==References== |
| + | <references/> |
| + | Animal Health & Production Compendium, '''Avian Infectious Bronchitis datasheet''', accessed 04/06/2011 @ http://www.cabi.org/ahpc/ |