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[[Category:To Do - Steph]]
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Also Known As — '''''Infectious coryza''''' — '''''Infectious Bronchitis''''' — '''''Infectious Proventriculitis''''' — '''''Avian Infectious Nephrosis''''' — '''''Avian Infectious Nephrosis'''''
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Caused By — ''Avian Infectious Bronchitis Virus'' — ''AIBV'' — ''ICTV'' — ''IBV'' — ''AIB'' — ''IB''
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==Introduction==
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Avian Infectious Bronchitis is a '''highly contagious''' viral disease primarily of the '''[[Respiratory System | respiratory system]]''' of birds, caused by a '''[[Coronaviridae | coronavirus]]'''.
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The virus can also cause damage to the '''[[Kidney Anatomy and Physiology | kidneys]]''' and '''[[Oviduct - Anatomy & Physiology | oviducts]]'''.
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IBV is transmitted mainly by '''aerosols''' and also by contaminated people/vehicles/equipment.
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It can become '''latent''' in a bird and recrudesce with '''stress''', e.g. at point of lay.
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This disease is notifiable to the World Organisation for Animal Health [http://www.oie.int/ {OIE)]
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==Signalment==
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Chickens, pigeons and pheasants are affected.
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Disease is most severe in chicks.
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==Distribution==
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Worldwide
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==Clinical Signs==
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'''Reduced weight gain''' or '''egg production''' and reluctance to move is often the first indicator of disease.
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'''Mortality''' often occurs due to secondary infection, particularly due to ''E. coli'' and ''Mycoplasma'' infections. Mortality is highest in intensively reared broiler flocks.
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'''Sneezing, Coughing, Dyspnoea''', Ingesta present in respiratory passages, Nasal discharge, Abnormal lung sounds on auscultation
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'''Diarrhoea, dehydration''', polydipsia
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'''Polyuria, Pollakiuria'''
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Reluctance to move
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Swelling of the head and face
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Conjunctival congestion and increased lacrimation or ocular discharge
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'''Soft egg shells''', thin albumin and watery yolks
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Neurological signs
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==Diagnosis==
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In the acute phase, '''viral isolation''' can be attempted from eggs, tracheal swabs or tracheal/lung biopsies.
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If more than one week after initial infection, caecal tonsils or cloacal swabs are more reliable.
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'''RT-PCR''' can be performed on buccal or oropharyngeal swabs but will not differentiate live from dead virus isolate
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'''Agar Gel Precipitation''' and '''Immunofluorescent Antibody''' (IFAT) tests can also be used to detect virus.
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On '''post-mortem examination''', '''yellow catarrhal or caseous exudates''' are present in the trachea, nasal passages, sinuses and air sacs.
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On histopathology of the trachea, loss of cilia and sloughing with '''[[Heterophils | heterophilic infiltration]]''' is evident.
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The kidneys are '''pale and swollen''' and tubules distended with '''urates''' if nephritis is also present. Heterophilic inflammation and degeneration may be evident.
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Detection of '''viral antibodies''' is also valuable in surveillance, monitoring of vaccination and identification of latently infected birds. This can be performed using '''Agar Gel Immunodiffusion''' (AGID) , [[ELISA testing | ELISA]], Virus Neutralisation (VN) and Haemagglutination-Inhibition (HI).
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RT-PCR, VN and HI can also be used to type IBV isolates.
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==Treatment==
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'''No treatment''' is available for the viral infection.
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Use of '''antibiotics''' in drinking water to treat and prevent secondary infection may reduce mortality and losses.
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==Control==
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'''Live and Killed IBV vaccines''' are available and widely used but cross-protection is poor and numerous serotypes exist so disease is not always prevented. Vaccinations can be administered as intra-muscular injections or sprays. Killed vaccines used alone do not induce immunity and therefore live vaccines are required to prime immunity first.
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Good biosecurity and hygiene protocols are imperative to control of this highly contagious disease. Particular efforts should be made with respect to '''ventilation''' and '''air quality'''.
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==References==
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<references/>
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Animal Health & Production Compendium, '''Avian Infectious Bronchitis datasheet''', accessed 04/06/2011 @ http://www.cabi.org/ahpc/
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