A prion (PrP) is a protein that occurs normally in the nervous and lymphoreticular tissues. When is changes conformation (PrP<sup>sc</sup>/PrP<sup>Res</sup>) it becomes an infectious agent and causes degeneration of neurological tissue. | A prion (PrP) is a protein that occurs normally in the nervous and lymphoreticular tissues. When is changes conformation (PrP<sup>sc</sup>/PrP<sup>Res</sup>) it becomes an infectious agent and causes degeneration of neurological tissue. |