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Chicken Anaemia Virus Disease Flashcards (view source)
Revision as of 10:22, 29 June 2011
, 10:22, 29 June 2011no edit summary
*VP1 (52kDA) - structural protein; intracellular form of the capsid protein
*VP1 (52kDA) - structural protein; intracellular form of the capsid protein
*VP2 (24 kDA) - found in small amounts in the purified virus
*VP2 (24 kDA) - found in small amounts in the purified virus
*VP3 (14 kDA) - involved in apoptosis (programmed and controlled cell death with no lysis of the cell. Causes apoptosis of infected stem cells in the bone marrow (BM). Sequential damage to BM inhibits the production of red blood cells (RBC), white blood cells (WBC), lymphoid tissue and platelets
*VP3 (14 kDA) - involved in apoptosis (programmed and controlled cell death with no lysis of the cell. Causes apoptosis of infected stem cells in the bone marrow (BM). Sequential damage to BM inhibits the production of red blood cells (RBC), white blood cells (WBC), lymphoid tissue and platelets
Due to its apoptotic properties VP3 has the potential to be an anti-cancer agent
-Vaccines need to contain both VP1 and VP2 to be antigenic.
-Due to VP3 apoptotic properties it has the potential to be an anti-cancer agent.
|l5=Chicken Anaemia Virus Disease#Introduction
|l5=Chicken Anaemia Virus Disease#Introduction