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Both modified live and beta-propiolactone inactivated BVDV vaccines are available for used. Although cross-protection between strains and genotypes is generally good, antigenic diversity among challenge viruses may affect the efficacy of a given vaccine. Because BVDV is tropic for the foetus, modified live vaccines should not be used in pregnant animals. The virus is also immunosuppressive and so vaccination of animals showing signs of disease is not recommended. Maternally-derived antibody wanes at 3-6 months of age, and so to ensure that vaccination induces a protective immune response animals should be vaccinated (or re-vaccinated) after this age.
Both modified live and beta-propiolactone inactivated BVDV vaccines are available for used. Although cross-protection between strains and genotypes is generally good, antigenic diversity among challenge viruses may affect the efficacy of a given vaccine. Because BVDV is tropic for the foetus, modified live vaccines should not be used in pregnant animals. The virus is also immunosuppressive and so vaccination of animals showing signs of disease is not recommended. Maternally-derived antibody wanes at 3-6 months of age, and so to ensure that vaccination induces a protective immune response animals should be vaccinated (or re-vaccinated) after this age.
==Literature Search==
==Links==
*[http://www.rvc.ac.uk/bvd/Index.cfm Royal Veterinary College BVD page]
*[http://www.scotland.gov.uk/Publications/2010/06/29143957/1 Bovine Viral Diarrhoea (BVD): An Eradication Scheme for Scotland - Consultation Paper]
[http://www.cabi.org/cabdirect/FullTextPDF/2007/20073161537.pdf '''Bovine viral diarrhoea: an emerging disease of ruminants in India.''' Richa Sood; Intas Pharmaceuticals Ltd, Ahmedabad, India, Intas Polivet, 2007, 8, 1, pp 145-152, 37 ref. - '''Full Text Article''']
{{Learning
|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=title:(%22bovine%22)+AND+title:(vir*)+AND+title:(diar*)&occuring1=title&rowId=2&options2=OR&q2=BVD&occuring2=title&rowId=3&options3=OR&q3=%22Mucosal+disease%22&occuring3=title&rowId=4&options4=OR&q4=BVDV&occuring4=title&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=62&y=8 Bovine Viral Diarrhoea Virus publications]
|full text = [http://www.cabi.org/cabdirect/FullTextPDF/2007/20073161537.pdf '''Bovine viral diarrhoea: an emerging disease of ruminants in India.''' Richa Sood; Intas Pharmaceuticals Ltd, Ahmedabad, India, Intas Polivet, 2007, 8, 1, pp 145-152, 37 ref.]
}}
==References==
==References==